Applying chemistry principles towards the study and manipulation of biological systems
DECEMBER 2023
- Congrats to Miaomiao, Myungsun, and Timothy on publishing on the regulatory role of endocannabinoid biosynthetic enzymes in modulating pain response through the AMPK signaling pathway in PNAS. A big thanks to the Akbarali, Lichtman, and Leitinger groups for collaborating on this paper!
- Welcome to our new postdoctoral fellow Alexis Edwards!
NOVEMBER 2023
- Thank you Jen Liou for the invitation to present our work on lipid signaling and macrophage bioenergetics in the Department of Physiology at UTSW.
- 6 new graduate students join the Hsu Family: Mikayla Horvath, Payton Lowrey, Harith Budaraju, Surya Mookherjee, Wes Wolfe and Yen-Ting Chen. Welcome!
- Welcome to our new postdoctoral fellow Changlei Zhu!
OCTOBER 2023
Biocentury writeup
UT Austin highlight
UVA LVG highlight
- We are excited to see the launch of Hyku Biosciences to explore the drug discovery potential of SuTEx!
Biocentury writeup
UT Austin highlight
UVA LVG highlight
- Congrats to Andy Heindel on publishing the development of a chemoproteomic platform for investigating RNA binding activity proteins with site specificity and proteome-wide coverage in Nature Communications. A wonderful collaboration with the Hafner and Harris groups. A nice highlight from UT Austin can be found here.
SEPTEMBER 2023
- A big thanks to Sid Hecht for the invitation to visit and present our work on SuTEx chemistry at the School of Molecular Science at ASU.
- Thank you to the organizers for the opportunity to present our work on chemical strategies for profiling the protein-RNA interactome at Discovery on Target.
- Welcome Anting Chen as our new lab manager. Anting has a background in chemistry and an avid champion of career development and STEM. We look forward to having Anting help us achieve our mission here at UT Austin!
- Welcome to our new research scientist Emily Ayers!
AUGUST 2023
- The Hsu Lab has completed the move to UT Austin. Hook 'em Horns!
- Welcome to our new postdoctoral fellow Neelesh Reddy!
JULY 2023
- Thank you to organizers for the opportunity to present our work on endocannabinoid biosynthetic enzyme regulation of inflammation and pain at Cannabinoid Function in the CNS GRC in Spain.
- Thank you to organizers for the invitation to present our work on diacylglycerol kinase investigations using chemoproteomics and protein engineering at the Molecular and Cellular Biology of Lipids GRC.
JUNE 2023
- Thank you to organizers for the opportunity to present our work on SuTEx chemistry for chemical biology and protein ligand discovery at Bioorganic Chemisry GRC .
MAY 2023
- Congrats to Anthony and Miaomiao on publishing their work on discovery of SuTEx as condensate-modulating covalent ligands in JACS. A big thanks Ralph Kleiner and Josh Seo for the excellent collaboration!
- Congrats to Rob Mendez on publishing his work combining chemoproteomics and AlphaFold to map ligandable pockets on the diacylglycerol kinase superfamily in RSC Chemical Biology.
APRIL 2023
- Thank you to the organizers for the opportunity to present our work on chemoproteomic methods for investigating the RNA interactome at Drug Discovery Chemistry.
MARCH 2023
- Thanks to Phil Jones for the invitation to visit and present our work at Institute for Applied Cancer Science and Department of Genomic Medicine at MD Anderson Cancer Center.