NEWS
OCTOBER 2023
Biocentury writeup
UT Austin highlight
UVA LVG highlight
- We are excited to see the launch of Hyku Biosciences to explore the drug discovery potential of SuTEx!
Biocentury writeup
UT Austin highlight
UVA LVG highlight
- Congrats to Andy Heindel on publishing the development of a chemoproteomic platform for investigating RNA binding activity proteins with site specificity and proteome-wide coverage in Nature Communications. A wonderful collaboration with the Hafner and Harris groups. A nice highlight from UT Austin can be found here.
SEPTEMBER 2023
- A big thanks to Sid Hecht for the invitation to visit and present our work on SuTEx chemistry at the School of Molecular Science at ASU.
- Thank you to the organizers for the opportunity to present our work on chemical strategies for profiling the protein-RNA interactome at Discovery on Target.
- Welcome Anting Chen as our new lab manager. Anting has a background in chemistry and an avid champion of career development and STEM. We look forward to having Anting help us achieve our mission here at UT Austin!
- Welcome to our new research scientist Emily Ayers!
AUGUST 2023
- The Hsu Lab has completed the move to UT Austin. Hook 'em Horns!
- Welcome to our new postdoctoral fellow Neelesh Reddy!
JULY 2023
- Thank you to organizers for the opportunity to present our work on endocannabinoid biosynthetic enzyme regulation of inflammation and pain at Cannabinoid Function in the CNS GRC in Spain.
- Thank you to organizers for the invitation to present our work on diacylglycerol kinase investigations using chemoproteomics and protein engineering at the Molecular and Cellular Biology of Lipids GRC.
JUNE 2023
- Thank you to organizers for the opportunity to present our work on SuTEx chemistry for chemical biology and protein ligand discovery at Bioorganic Chemisry GRC .
MAY 2023
- Congrats to Anthony and Miaomiao on publishing their work on discovery of SuTEx as condensate-modulating covalent ligands in JACS. A big thanks Ralph Kleiner and Josh Seo for the excellent collaboration!
- Congrats to Rob Mendez on publishing his work combining chemoproteomics and AlphaFold to map ligandable pockets on the diacylglycerol kinase superfamily in RSC Chemical Biology.
APRIL 2023
- Thank you to the organizers for the opportunity to present our work on chemoproteomic methods for investigating the RNA interactome at Drug Discovery Chemistry.
MARCH 2023
- Thanks to Phil Jones for the invitation to visit and present our work at Institute for Applied Cancer Science and Department of Genomic Medicine at MD Anderson Cancer Center.
FEBRUARY 2023
- Happy to share our review article on functional tyrosine profiling dedicated to Ben Cravatt on the occasion of being awarded the 2022 Wolf Prize in Chemistry.
JANUARY 2023
- We begin 2023 with celebration of new R01 funding from the National Institute of Allergy and Infectious Diseases (NIAID). We thank the NIH and scientific community for the continued support of our research group!
DECEMBER 2022
- Congrats to Anthony Ciancone on publishing his work to identify stress-responsive tyrosine and lysine sites involved in biomolecular condensate regulation including functional annotation of the EDC3 Y475 site. You can read the full story here.
- Thank you to Huaibin Cai at NIH and organizers for the invitation to present our DAGLB work in the webinar on Endocannabinoid System and Brain Diseases.
NOVEMBER 2022
- Congrats to Dr. Kun Yuan on successfully defending his thesis. We enjoyed a nice celebration with the Hsu Lab crew! We wish you the best of luck Kun at your new scientist position at BioMarin Pharmaceutical.
OCTOBER 2022
- Looking forward to visiting New York for The Mark Foundation for Cancer Research Annual Scientific Symposium. Looking forward to presenting in the Advances in Chemical Biology Session alongside my colleagues Angela Koehler and Eric Fischer.
- Thank you to the organizing committee of Discovery of Target for the invitation to share our work on SuTEx chemistry in the recent meeting in Boston.
- Congrats to Dr. Anthony Ciancone on successful defense of his thesis. Great celebration with a fantastic crew! Good luck Anthony on your postdoctoral position at NCI in the O’Reilly laboratory.
SEPTEMBER 2022
- We thank The Daily Texan on their article about our CPRIT Award and recruitment to UT Austin Chemistry!
AUGUST 2022
- Professor Hsu receives a CPRIT Rising Stars Award and will move his research program to the Chemistry Department at UT Austin in 2023 as a CPRIT Scholar. The official announcement can be found at CPRIT, UT Austin Chemistry, and UT College of Natural Sciences.
JULY 2022
- Congrats to Dr. Rob Mendez for successfully defending his thesis. Glad we had a chance to celebrate a successful defense through a nice outdoor lab party. We wish you luck Rob in your postdoctoral position at Brown University!
JUNE 2022
- Thank you to Rebecca Berdeaux and Alan Smrcka for the invitation to speak at the GRC Phosphorylation and G-Protein Mediated Signaling Networks Meeting!
- Our collaborative work with the Adli and Kashatus group investigating ISL2 in pancreatic cancer is published in Developmental Cell.
MAY 2022
- A big thanks to Donita Brady, Arvin Dar, and organizers for the invitation to speak at the FASEB Conference on Cell Signaling in Cancer!
- Our collaborative work with the Adli and Kashatus group investigating ISL2 in pancreatic cancer is published in Developmental Cell.
APRIL 2022
- Enjoyed presenting SuTEx platform at the Drug Discovery Chemistry Meeting in San Diego!
- We are thrilled to welcome back undergraduate student researchers to the group. Our newest lab members are Caitlin McSorley and Robert Seal
MARCH 2022
- Thanks to Georg Winter for the invite to give a virtual talk at CeMM.
- Excited to give a talk at the MRA Annual retreat!
- Looking forward to presenting our latest work on developing lipid kinase inhibitors and catching up with colleagues at the ACS Meeting in San Diego.
FEBRUARY 2022
- Welcome to our newest graduate student David Leace from the UVA MD/PhD program!
JANUARY 2022
- New review on electrophilic groups used in covalent probe and therapeutic development. Congrats to leading author Justin!
DECEMBER 2021
- We end the year with a celebration of new funding from NIH. I am proud of my team for overcoming challenging times and grateful for all of our accomplishments. Looking forward to a bright new year!
NOVEMBER 2021
- We welcome our newest Postdoctoral Fellow Minhaj Shaikh and Graduate Student Madeleine Ware. We are excited to have you both join our team!
SEPTEMBER 2021
- We welcome our newest Postdoctoral Fellows Justin Grams and Xiaoding Jiang. We are excited to have you join our team!
AUGUST 2021
- Congrats to Kun and Becca's publication on development of a targeted covalent kinase probe in Analytical Chemistry! Also a big thanks to the Hunt lab for the collaboration. Read the article here.
JULY 2021
- Happy to share our new review on enabling investigations of the lipid kinome using chemical proteomic technologies. Congrats to Tim on this publication in Current Opinion in Chemical Biology.
- Congratulations Dr. Adam Borne. We wish you the best in your new position as Senior Proteomics Scientist at Roivant. See our celebration.
JUNE 2021
- Congratulations Dr. Tim Ware. We wish you the best in your postdoctoral fellow position in the Cravatt Lab! Very thankful our group could meet safely after a long year of lockdown. See our celebration.
MAY 2021
- Tim Ware defends his thesis titled "Characterization of diacylglycerol metabolizing enzyme functional specificity in native biological systems." Congrats Tim!
APRIL 2021
- Congrats to Anthony, Emmanuel, Hahm, Skylar, and the SuTEx team on the new publication in ChemBioChem!
FEBRUARY 2021
- Professor Hsu is selected as a recipient of the Emerging Leader Award from The Mark Foundation for Cancer Research! Read the press release here.
- Congrats to our graduate students Miaomiao Chen and Michael Founds for passing their candidacy exams. Way to go!
- Congrats to Tim Ware for receiving an NIH F31 Ruth L. Kirschstein Predoctoral Individual National Research Service Award! Read the highlight on the departmental website here.
- Our preview on chemical proteomics for target deconvolution in phenotypic drug discovery from the Pfizer group. Read the highlight in Cell Chemical Biology here.
JANUARY 2021
- Congrats to Tao, Mohsen, Adam, and Jeff and collaborators on their research article describing development of a sulfonyl-triazole probe for live cell kinase profiling!
- Congrats to Adam, Jeff, and Kun, on their review article on SuTEx and its chemical biology applications!
DECEMBER 2020
- We welcome our new graduate students Olivia Murtagh and Larry Reser!
NOVEMBER 2020
- Glad to see our collaborative work with the Laurie lab published in Journal of Biological Chemistry.
OCTOBER 2020
- Great job to the Gaultier Lab and my student Becca McCloud for this collaborative effort on PKM2. Read the story here in Science Signaling.
AUGUST 2020
- Congrats to Dr. Toroitich! We wish you the best of luck in your future career.
JULY 2020
- Proud to announce my former postdoc Sean Campbell has started his new position as Assistant Professor of Pathology at Albert Einstein!
JUNE 2020
- I received official approval for my tenure and promotion to Associate Professor!
MAY 2020
- Congrats to Dr. Brulet! Jeff was our first student to graduate via a virtual ceremony. Check out the ceremony here. Good luck on your future position as a Scientist at Scorpion Therapeutics!
APRIL 2020
- Congrats to Jeff Brulet on his efforts to apply SuTEx for developing tyrosine-reactive covalent ligands of proteins. Read our findings at JACS!
MARCH 2020
- We thank Clinical OMICs for highlighting our research program. Honored to be a part of the selected group.
FEBRUARY 2020
- Congrats to Tim Ware and his amazing efforts to combine protein engineering and lipidomics to annotate C1 domain function in directing lipid kinase fatty acyl specificity. Read our findings at Nature Chemical Biology!
JANUARY 2020
- Looking forward to another great year!
- Congrats to Rob and his collaborative efforts with the Ewald Lab. Very nice story on Spatially Targeted Optical Microproteomics (STOMP).
DECEMBER 2019
- Annual Hsu Lab Christmas Party. A heartfelt thanks for all the hard work and dedication from the members of my group in 2019!
NOVEMBER 2019
- Congrats to Hahm, Emmanuel, Adam, and Jeff on their tremendous effort to develop SuTEx chemistry for chemical proteomic investigation of functional tyrosines. Read our findings at Nature Chemical Biology!
OCTOBER 2019
- Prof Hsu will present a talk in the Advancements in Chemical Biology session at SERMACS.
SEPTEMBER 2019
- Congrats to Rebecca McCloud on our collaborative paper with the Lazo group in Journal of Pharmacology and Experimental Therapeutics.
AUGUST 2019
- Congrats to Caroline on her paper in Current Protocols in Chemical Biology.
- Congrats to Tim and Shin on their paper in Methods in Enzymology.
JULY 2019
- Prof Hsu will present a talk at the Gordon Research Conference on Enzymes, Coenzymes and Metabolic Pathways
JUNE 2019
- Jeff, Adam, and Tim present posters at the Gordon Research Conference on High Throughput Chemistry and Chemical Biology.
- Prof Hsu will present a poster at the Bioorganic Chemistry Gordon Research Conference.
MAY 2019
- Congrats Dr. Shin and Dr. Franks. Official first PhDs from the Hsu Lab!
APRIL 2019
- A huge congrats to Shin and Caroline for defending their thesis! The Lab celebrates this great accomplishment.
- Congrats to Kelly for being selected a recipient of the 2019 Minerva Scholars Award.
- Congrats to Skylar and Rebecca S for receiving a departmental Undergraduate Summer Research Scholarship.
MARCH 2019
- Congrats to Anthony, Kun, and Rob for passing their Candidacy exam. They are officially PhD candidates. Great job!
FEBRUARY 2019
- Rebecca M is selected as the 2019 Adam Ritchie Outstanding Graduate Student. Great job!
DECEMBER 2018
- Ending a great year with the annual Hsu Lab Christmas Party!
NOVEMBER 2018
- Thank you to METRIC and Thermo Scientific for the invitation and opportunity to speak at the Annual RTP Mass Spectrometry Symposium!
OCTOBER 2018
- We thank the UVA Cancer Center for awarding our lab a Collaboration Award to support cross-grounds efforts to study and target DGKs!
SEPTEMBER 2018
- Congrats to Sean, Caroline, Adam, Shin, and Liuzhi on their paper in Molecular Pharmacology!
AUGUST 2018
- Professor Hsu will be presenting a talk in the Advances in Mass Spectrometry session at the ACS National Meeting in Boston.
- Professor Hsu will be presenting a talk in the Early Career Investigators in Biological Chemistry session at the ACS National Meeting in Boston.
- Congrats to Adam, Tao, Becca, and Boobalan on their paper in Current Topics in Microbiology and Immunology!
- Congrats to Shin and Tim on their paper in Biochimica et Biophysica Acta!
JULY 2018
- Congrats to Adam Borne for receiving a Wagner Fellowship Award!
- Welcome our new graduate student Kun!
- Professor Hsu attends GRC Enzymes, Coenzymes, and Metabolic Pathways.
June 2018
- Hsu lab is heading to GRC Bioorganic this summer. Caroline and Shin will be presenting their research at the associated Gordon Research Seminar.
- Congrats Sean on your new position as Assistant Director of Hematology and Coagulation Labs at the Montefiore Medical Center. Good luck in your new position!
- Congrats to Sean for receiving a 2018 ACLPS Paul E. Strandjord Young Investigator Award!
May 2018
- Professor Hsu is selected to receive a Young Investigator Award. We thank the Melanoma Research Alliance for their generous support to find new immuno-oncology targets using chemoproteomic technologies!
APRIL 2018
- Professor Hsu is traveling to sunny San Diego for the ASBMB meeting.
- Professor Hsu will travel to the windy city for the annual AACR meeting.
- Congratulations to Rebecca McCloud for being awarded a NSF GRFP Fellowship!
- Welcome our new graduate student Andy Heindel!
MARCH 2018
- Professor Hsu visits the Pharmacology and Toxicology Department at VCU to present a seminar.
- Professor Hsu will give an oral presentation in the Biological Chemistry session of the 255th ACS National Meeting in New Orleans!
- Caroline and Shin will present posters on their exciting thesis work at the 255th ACS National Meeting in New Orleans!
FEBRUARY 2018
- Professor Hsu visits the Biochemistry Department at Virginia Tech to present a seminar.
- Congrats to Caroline on being selected a 2018 Sidney M. Hecht Graduate Fellow!
JANUARY 2018
- Welcome our new postdoctoral fellows Tao and Boobalan!
- Congrats to Shin and Caroline on their ERK paper in Chemical Science!
2017
DECEMBER 2017
- Annual Hsu Lab Christmas Party. Thanks to everyone for another great year!
- Congratulations to Rebecca, Caroline, and Sean on their DGK paper in Biochemistry!
NOVEMBER 2017
- Welcome our new graduate student Anthony Ciancone!
- Congratulations to Caroline on receiving an American Chemical Society Women Chemists Travel Award sponsored by Eli Lilly & Company!
- Welcome our new undergraduate students Haley, Amrita, Sajan, and Elizabeth!
OCTOBER 2017
- Lab celebration for recent grants and papers!
- The Hsu Lab is featured in UVa Today on their recent Department of Defense CDMRP Award!
- The Hsu Lab receives their first NIH R01 Grant!!! We are very grateful for the support!
SEPTEMBER 2017
AUGUST 2017
JULY 2017
- Congratulations to Shin on his liposomal DAGLB inhibitor paper in Molecular Pharmaceutics!
AUGUST 2017
- Our DGK paper in Cell Chemical Biology is highlighted on the ASBMB Lipid Corner! Video here.
- Hsu lab along with UVa collaborators BJ Purow and Thurl Harris receive a Schiff Grant to study DGKs in GBM!
JULY 2017
- Congratulations to Caroline and Sean on their DGK paper in Cell Chemical Biology!
JUNE 2017
MAY 2017
APRIL 2017
MARCH 2017
FEBRUARY 2017
- Adam is selected for the UVa Cancer Research Training Grant.
- Tim is selective for the UVa Molecular Biophysics Training Grant.
MAY 2017
- Congratulations to Liuzhi Zhang for receiving an Alpha Chi Sigma Undergraduate Chemistry Award!
APRIL 2017
- Congratulations to Caroline for winning 1st place in the 3rd Year Poster Award for her work on diacylglycerol kinases
MARCH 2017
- Professor Hsu is selected as a recipient of the DOD 2016 Peer Reviewed Cancer Research Program Career Development Award!
- Welcome our new graduate student Adam Borne!
FEBRUARY 2017
- Sean is selected for the UVA Cancer Research Training Grant.
2016
DECEMBER 2016
NOVEMBER 2016
OCTOBER 2016
SEPTEMBER 2016
JUNE 2016
APRIL 2016
MARCH 2016
FEBRUARY 2016
JANUARY 2016
NOVEMBER 2016
- Welcome our new postdoctoral fellow Sean Campbell!
- Welcome our new graduate students Tim Ware and Rebecca McCloud!
- Welcome our new undergraduate students Liuzhi Zhang and Victoria Kim!
OCTOBER 2016
- Congratulations to Natalie Gaughan on her new Staff Scientist position at NIAID!
SEPTEMBER 2016
- The Hsu lab receives a Biomedical Innovation in Diabetes Grant from UVA LaunchPad. We are very grateful to the Manning Family Foundation for the support!
JUNE 2016
- Jeff is selected for the UVA Pharmacological Sciences Training Grant
- Caroline is reappointed to the UVA Pharmacological Sciences Training Grant
APRIL 2016
- Congratulations to Youlim for winning second place in the ACS Undergraduate Poster Session!
MARCH 2016
- New paper identifies diacylglycerol lipase-beta as a novel target for inflammatory and neuropathic pain.
FEBRUARY 2016
- Congratulations to Caroline and Shin for passing their 2nd year candidacy exams!
JANUARY 2016
- New paper in PNAS describing DAGL function in nicotine addiction.
2015
DECEMBER 2015
SEPTEMBER 2015
AUGUST 2015
SEPTEMBER 2015
- Welcome Youlim to the lab
- Welcome Weihao to the lab.
- Welcome Hahm and Carolyn to the lab.
AUGUST 2015
- End of summer BBQ to celebrate everyone's hard work!
- Caroline selected for the UVA Pharmacological Sciences Training Grant
- Welcome our new undergraduate researcher Jack Hawkins.
- New paper from the Hsu lab identifies potent and selective inhibitors of platelet-activating factor acetylhydrolases by high-throughput screening.
- Welcome our new research scientist Mark Ross! Mark brings 20+ years of mass spectrometry experience to our research group.
- Welcome our new graduate students: Myungsun Shin, Caroline Franks, and Jeffrey Brulet!
- Renovations in the Hsu Lab are underway!