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The Hsu Laboratory focuses on the discovery of bioactive molecules. A central theme of our group is the development of covalent probes and inhibitors for investigating protein and lipid activity. Our research is multidisciplinary and uses a combination of organic synthesis, bioanalytical chemistry, and bioorganic chemistry. Current efforts include identifying new reactive chemistry, quantifying ligandability of proteins on a proteomic scale, and deciphering structure and function of membrane signals in living systems. Ultimately, we aim to develop new molecules to enable chemical biology and therapeutic discovery.

Molecular recognition, enzymatic regulation, and therapeutic potential of lipid signaling

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Reactive chemistry for assessing ligandability of the proteome for therapeutic discovery

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© Copyright 2015 | Hsu Laboratories | Department of Chemistry | University of Texas at Austin                                                                              Updated 12/14/2023
100 E 24th St | Austin, Texas 78712 | Contact Us
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